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- Title
Resolving multiple epigenetic pathways to adolescent depression.
- Authors
Eaves, Lindon; Silberg, Judy; Erkanli, Alaattin
- Abstract
Genotype x environment interaction (G x E) arises when genes influence sensitivity to the environment. G x E is easily recognized in experimental organisms that permit randomization of genotypes over fixed environmental treatments. Genotype-environment correlation (rGE) arises when genetic effects create or evoke exposure to environmental differences. Simultaneous analysis of G x E and such 'active' or 'evocative' rGE in humans is intractable with linear structural models widely used in behavioral genetics because environments are random effects often correlated with genotype. The causes of the environmental variation, therefore, need to be modeled at the same time as the primary outcome.
- Publication
Journal of child psychology and psychiatry, and allied disciplines, 2003, Vol 44, Issue 7, p1006
- ISSN
0021-9630
- Publication type
Journal Article
- DOI
10.1111/1469-7610.00185