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- Title
Ferrous sulfate-induced increase in requirement for thyroxine in a patient with primary hypothyroidism.
- Authors
Shakir, K M; Chute, J P; Aprill, B S; Lazarus, A A
- Abstract
Recent studies have shown that under experimental conditions ferrous sulfate may reduce the gastrointestinal absorption of orally administered levothyroxine sodium in patients with primary hypothyroidism. We describe a patient who became hypothyroid while taking ferrous sulfate. The hypothyroid status was corrected by increasing the dose of levothyroxine. Subsequently, when ferrous sulfate was discontinued, the patient became hyperthyroid while taking the higher dose of thyroid hormone preparation. Since both hypothyroidism and iron deficiency anemia may coexist, additional thyroid function testing is recommended in patients treated concurrently with ferrous sulfate and L-thyroxine.
- Publication
Southern medical journal, 1997, Vol 90, Issue 6, p637
- ISSN
0038-4348
- Publication type
Journal Article
- DOI
10.1097/00007611-199706000-00011