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Title
Clonidine normalizes sensorimotor gating deficits in patients with schizophrenia on stable medication.
Authors
Oranje, Bob; Glenthøj, Birte Y
Abstract
Cognitive deficits form core features in schizophrenia. Several studies have shown improvements in prefrontal cognitive function by α 2 -agonists in schizophrenia. In the present study, it was investigated whether clonidine (an α 2 -adrenoceptor agonist) could normalize sensorimotor gating deficits in schizophrenia.