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- Title
Anti-Toxoplasma gondii antibodies in patients with schizophrenia--preliminary findings in a Turkish sample.
- Authors
Cetinkaya, Zafer; Yazar, Suleyman; Gecici, Omer; Namli, Mustafa N
- Abstract
Schizophrenia is a serious neuropsychiatric disease of uncertain etiology. We investigated the seropositivity rate for anti-Toxoplasma IgG and IgM antibodies by enzyme-linked immunosorbent assay (ELISA) in patients with schizophrenia to ascertain a possible relationship between Toxoplasma gondii and schizophrenia. We selected 100 patients with schizophrenia, 50 with depressive disorder, and 50 healthy volunteers to investigate the seropositivity rate of anti-Toxoplasma antibodies by ELISA. The seropositivity rate for anti-Toxoplasma IgG antibodies among schizophrenia patients (66%) was significantly higher than among patients with depressive disorder or healthy volunteers (P < .01). Thus, there might be a causal relationship between toxoplasmosis and the etiology of schizophrenia.
- Publication
Schizophrenia bulletin, 2007, Vol 33, Issue 3, p789
- ISSN
0586-7614
- Publication type
Journal Article
- DOI
10.1093/schbul/sbm021