We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Weight gain associated with neuroleptic medication: a review.
- Authors
Stanton, J M
- Abstract
In this article we review the empirical literature on weight gain associated with neuroleptic drug use. Weight gain, which appears to be associated with an increase in appetite, is variable but likely to be larger initially and then plateau. Clozapine and low-potency phenothiazines are associated with the largest gains and molindone with weight loss, but the mechanism is not known. Amantadine and fenfluramine may reverse weight gain to some degree. Dietary fat seems to play an important role in obesity, and research is needed to increase the data base and elucidate possible mechanisms. Studies are also needed to evaluate preventive strategies and to determine which drugs are least likely to produce weight gain as well as which drugs could be added to a neuroleptic regimen to control weight.
- Publication
Schizophrenia bulletin, 1995, Vol 21, Issue 3, p463
- ISSN
0586-7614
- Publication type
Journal Article
- DOI
10.1093/schbul/21.3.463