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- Title
Reduced number of endothelial progenitor cells is predictive of early relapse in anti-neutrophil cytoplasmic antibody-associated vasculitis.
- Authors
Závada, Jakub; Kideryová, Lindy; Pytlík, Robert; Hrusková, Zdenka; Tesar, Vladimír
- Abstract
ANCA-associated vasculitis (AAV) is an inflammatory disorder of small- to medium-sized vessels with relapsing/remitting progression. Microvascular endothelial injury is a major feature of AAV. Circulating endothelial progenitor cells (EPCs) may provide an endogenous repair mechanism to counteract ongoing endothelial damage. We hypothesized that decreased capacity for endothelial regeneration paralleled by low EPC numbers could increase the risk of relapse in patients with AAV.
- Publication
Rheumatology (Oxford, England), 2009, Vol 48, Issue 10, p1197
- ISSN
1462-0332
- Publication type
Journal Article
- DOI
10.1093/rheumatology/kep130