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- Title
Mycophenolate mofetil is as efficacious as, but safer than, cyclophosphamide in the treatment of proliferative lupus nephritis: a meta-analysis and meta-regression.
- Authors
Mak, Anselm; Cheak, Alicia A C; Tan, Jason Y S; Su, Hnin Cho; Ho, Roger C M; Lau, Chak Sing
- Abstract
Since mycophenolate mofetil (MMF) has emerged as an immunosuppressant for treating proliferative lupus nephritis, the role of cyclophosphamide (CYC)-containing regimens is being challenged. Efficacy data from randomized controlled trials (RCTs) and previous meta-analyses comparing these two agents for treating lupus nephritis have been inconsistent as they were heterogeneous in design and of small sample size. An updated meta-analysis is therefore required.
- Publication
Rheumatology (Oxford, England), 2009, Vol 48, Issue 8, p944
- ISSN
1462-0332
- Publication type
Journal Article
- DOI
10.1093/rheumatology/kep120