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- Title
Association of Genetic Factors With Selected Measures of Physical Performance.
- Authors
Thompson, William R.; Binder-Macleod, Stuart A.
- Abstract
The article focuses on a study which examined the association of angiotensin-converting enzyme (ACE) and other genetic factors with selected measures of physical performance. ACE is part of the renin-angiotensin system. The gene catalyzes the conversion of the angiotensin I to produce angiotensin II. It also degrades the potent vasolidator bradykinin. The polymorphism of the ACE gene is classified by the presence or absence of a DNA sequence within the ACE gene. Possible associations of the ACE polymorphism have ben investigated to determine whether the I and D alleles of the ACE gene gives an advantage for athletic performance. Two theories have been posed regarding the possible physiological mechanisms involving the ACE I/D polymorphism The first theory is that the ACE polymorphism may later physical performance through a metabolic response associated with the I allele.
- Publication
Physical Therapy, 2006, Vol 86, Issue 4, p585
- ISSN
0031-9023
- Publication type
Academic Journal
- DOI
10.1093/ptj/86.4.585