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- Title
Clinical pharmacology research strategy for dissolvable tobacco products.
- Authors
Mishina, Elena V; Hoffman, Allison C
- Abstract
Dissolvable tobacco products (DTPs) are relatively new to the market. Some researchers and manufacturers describe them as finely ground tobacco that has been compressed into sticks, strips, and orbs that dissolve or disintegrate in the mouth and do not require spitting. While the pharmacokinetic profiles of nicotine and other tobacco-associated compounds and pharmacological effects of these products are complex, their clinical pharmacology has not been systematically evaluated. We reviewed the scientific literature regarding the known pharmacokinetic (PK) characteristics and pharmacodynamic (PD) effects of DTPs with the purpose of identifying research gaps and informing future studies.
- Publication
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014, Vol 16, Issue 3, p253
- ISSN
1469-994X
- Publication type
Journal Article
- DOI
10.1093/ntr/ntt182