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- Title
Preoperative dynamic contrast-enhanced MRI correlates with molecular markers of hypoxia and vascularity in specific areas of intratumoral microenvironment and is predictive of patient outcome.
- Authors
Jensen, Randy L; Mumert, Michael L; Gillespie, David L; Kinney, Anita Y; Schabel, Matthias C; Salzman, Karen L
- Abstract
Measures of tumor vascularity and hypoxia have been correlated with glioma grade and outcome. Dynamic contrast-enhanced (DCE) MRI can noninvasively map tumor blood flow, vascularity, and permeability. In this prospective observational cohort pilot study, preoperative imaging was correlated with molecular markers of hypoxia, vascularity, proliferation, and progression-free and overall patient survival.
- Publication
Neuro-oncology, 2014, Vol 16, Issue 2, p280
- ISSN
1523-5866
- Publication type
Journal Article
- DOI
10.1093/neuonc/not148