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- Title
Time trends in glioblastoma multiforme survival: the role of temozolomide.
- Authors
Dubrow, Robert; Darefsky, Amy S; Jacobs, Daniel I; Park, Lesley S; Rose, Michal G; Laurans, Maxwell S H; King, Joseph T, Jr
- Abstract
In 2005, maximum safe surgical resection, followed by radiotherapy with concomitant temozolomide (TMZ), followed by adjuvant TMZ became the standard of care for glioblastoma (GBM). Furthermore, a modest, but meaningful, population-based survival improvement for GBM patients occurred in the US between 1999 (when TMZ was first introduced) and 2008. We hypothesized that TMZ usage explained this GBM survival improvement.
- Publication
Neuro-oncology, 2013, Vol 15, Issue 12, p1750
- ISSN
1523-5866
- Publication type
Journal Article
- DOI
10.1093/neuonc/not122