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- Title
Distinct patterns of kidney and liver cyst growth in pkd2(WS25/-) mice.
- Authors
Doctor, R Brian; Serkova, Natalie J; Hasebroock, Kendra M; Zafar, Iram; Edelstein, Charles L
- Abstract
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease that results in the development of cystic kidneys and liver. Pkd2(WS25/-) mice are a key genetic mouse model of human ADPKD that recapitulate the 'molecular recessive' nature of human ADPKD. Providing the foundation for future long-term studies, the present work documents distinct patterns of long-term cyst growth in the kidneys and liver of male and female pkd2(WS25/-) mice.
- Publication
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Vol 25, Issue 11, p3496
- ISSN
1460-2385
- Publication type
Journal Article
- DOI
10.1093/ndt/gfq195