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- Title
Serum IL-17 and IL-23 levels and autoantigen-specific Th17 cells are elevated in patients with ANCA-associated vasculitis.
- Authors
Nogueira, Estela; Hamour, Sally; Sawant, Devika; Henderson, Scott; Mansfield, Nicholas; Chavele, Konstantia-Maria; Pusey, Charles D; Salama, Alan D
- Abstract
The Th17 subset has been implicated in the pathogenesis of a number of autoimmune diseases. However, little is known about its role in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV). We measured serum levels of IL-17A and associated upstream cytokines and the frequency of IL-17-producing autoantigen-specific T cells in patients with AAV.
- Publication
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Vol 25, Issue 7, p2209
- ISSN
1460-2385
- Publication type
Journal Article
- DOI
10.1093/ndt/gfp783