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- Title
Functional analyses indicate a pathogenic role of factor H autoantibodies in atypical haemolytic uraemic syndrome.
- Authors
Strobel, Stefanie; Hoyer, Peter F; Mache, Christoph J; Sulyok, Endre; Liu, Wei-Shih; Richter, Heiko; Oppermann, Martin; Zipfel, Peter F; Józsi, Mihály
- Abstract
Atypical haemolytic uraemic syndrome (aHUS) is associated with defective complement regulation. Recently, an autoimmune aHUS form has been described that is associated with complement factor H (CFH) autoantibodies. The aim of this study was to address the pathologic relevance of CFH autoantibodies in aHUS.
- Publication
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Vol 25, Issue 1, p136
- ISSN
1460-2385
- Publication type
Journal Article
- DOI
10.1093/ndt/gfp388