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- Title
Early renal and vascular changes in ADPKD patients with low-grade albumin excretion and normal renal function.
- Authors
Azurmendi, Pablo J; Fraga, Adriana R; Galan, Felicita M; Kotliar, Carol; Arrizurieta, Elvira E; Valdez, Marta G; Forcada, Pedro J; Stefan, Jose S Santelha; Martin, Rodolfo S
- Abstract
Autosomal dominant polycystic kidney disease (ADPKD) shows an increase in both urine monocyte chemoattractant protein-1 (MCP-1) and carotid intima-media thickness (CIMT) before changes in serum creatinine concentration. Although microalbuminuria is an index of disease progression, data on whether renal alterations and vascular remodelling are already present at normal or minimally increased levels of urine albumin excretion in early stages of the disease are lacking.
- Publication
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Vol 24, Issue 8, p2458
- ISSN
1460-2385
- Publication type
Journal Article
- DOI
10.1093/ndt/gfp136