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- Title
Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD).
- Authors
Zafar, Iram; Belibi, Franck A; He, Zhibin; Edelstein, Charles L
- Abstract
Short-term studies have demonstrated that rapamycin or everolimus treatment decreases cyst formation and improves renal function in animal models of polycystic kidney disease (PKD). Autosomal dominant polycystic kidney disease (ADPKD) patients would likely require life-long treatment with rapamycin.
- Publication
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Vol 24, Issue 8, p2349
- ISSN
1460-2385
- Publication type
Journal Article
- DOI
10.1093/ndt/gfp129