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- Title
OPTIC: orthologous and paralogous transcripts in clades.
- Authors
Heger, Andreas; Ponting, Chris P
- Abstract
The genome sequences of a large number of metazoan species are now known. As multiple closely related genomes are sequenced, comparative studies that previously focussed on only pairs of genomes can now be extended over whole clades. The orthologous and paralogous transcripts in clades (OPTIC) database currently provides sets of gene predictions and orthology assignments for three clades: (i) amniotes, including human, dog, mouse, opossum, platypus and chicken (17 443 orthologous groups); (ii) a Drosophila clade of 12 species (12 889 orthologous groups) and (iii) a nematode clade of four species (13 626 orthologous groups). Gene predictions, multiple alignments and phylogenetic trees are freely available to browse and download from http://genserv.anat.ox.ac.uk/clades. Further genomes and clades will be added in the future.
- Publication
Nucleic acids research, 2008, Vol 36, Issue Database issue, pD267
- ISSN
1362-4962
- Publication type
Journal Article
- DOI
10.1093/nar/gkm852