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- Title
Human protein reference database--2006 update.
- Authors
Mishra, Gopa R; Suresh, M; Kumaran, K; Kannabiran, N; Suresh, Shubha; Bala, P; Shivakumar, K; Anuradha, N; Reddy, Raghunath; Raghavan, T Madhan; Menon, Shalini; Hanumanthu, G; Gupta, Malvika; Upendran, Sapna; Gupta, Shweta; Mahesh, M; Jacob, Bincy; Mathew, Pinky; Chatterjee, Pritam; Arun, K S; Sharma, Salil; Chandrika, K N; Deshpande, Nandan; Palvankar, Kshitish; Raghavnath, R; Krishnakanth, R; Karathia, Hiren; Rekha, B; Nayak, Rashmi; Vishnupriya, G; Kumar, H G Mohan; Nagini, M; Kumar, G S Sameer; Jose, Rojan; Deepthi, P; Mohan, S Sujatha; Gandhi, T K B; Harsha, H C; Deshpande, Krishna S; Sarker, Malabika; Prasad, T S Keshava; Pandey, Akhilesh
- Abstract
Human Protein Reference Database (HPRD) (http://www.hprd.org) was developed to serve as a comprehensive collection of protein features, post-translational modifications (PTMs) and protein-protein interactions. Since the original report, this database has increased to >20 000 proteins entries and has become the largest database for literature-derived protein-protein interactions (>30 000) and PTMs (>8000) for human proteins. We have also introduced several new features in HPRD including: (i) protein isoforms, (ii) enhanced search options, (iii) linking of pathway annotations and (iv) integration of a novel browser, GenProt Viewer (http://www.genprot.org), developed by us that allows integration of genomic and proteomic information. With the continued support and active participation by the biomedical community, we expect HPRD to become a unique source of curated information for the human proteome and spur biomedical discoveries based on integration of genomic, transcriptomic and proteomic data.
- Publication
Nucleic acids research, 2006, Vol 34, Issue Database issue, pD411
- ISSN
1362-4962
- Publication type
Journal Article
- DOI
10.1093/nar/gkj141