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- Title
TreeFam: a curated database of phylogenetic trees of animal gene families.
- Authors
Li, Heng; Coghlan, Avril; Ruan, Jue; Coin, Lachlan James; Hériché, Jean-Karim; Osmotherly, Lara; Li, Ruiqiang; Liu, Tao; Zhang, Zhang; Bolund, Lars; Wong, Gane Ka-Shu; Zheng, Weimou; Dehal, Paramvir; Wang, Jun; Durbin, Richard
- Abstract
TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as well as reliable ortholog and paralog assignments. Curated families are being added progressively, based on seed alignments and trees in a similar fashion to Pfam. Release 1.1 of TreeFam contains curated trees for 690 families and automatically generated trees for another 11 646 families. These represent over 128 000 genes from nine fully sequenced animal genomes and over 45 000 other animal proteins from UniProt; approximately 40-85% of proteins encoded in the fully sequenced animal genomes are included in TreeFam. TreeFam is freely available at http://www.treefam.org and http://treefam.genomics.org.cn.
- Publication
Nucleic acids research, 2006, Vol 34, Issue Database issue, pD572
- ISSN
1362-4962
- Publication type
Journal Article
- DOI
10.1093/nar/gkj118