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- Title
A new generation of JASPAR, the open-access repository for transcription factor binding site profiles.
- Authors
Vlieghe, Dominique; Sandelin, Albin; De Bleser, Pieter J; Vleminckx, Kris; Wasserman, Wyeth W; van Roy, Frans; Lenhard, Boris
- Abstract
JASPAR is the most complete open-access collection of transcription factor binding site (TFBS) matrices. In this new release, JASPAR grows into a meta-database of collections of TFBS models derived by diverse approaches. We present JASPAR CORE--an expanded version of the original, non-redundant collection of annotated, high-quality matrix-based transcription factor binding profiles, JASPAR FAM--a collection of familial TFBS models and JASPAR phyloFACTS--a set of matrices computationally derived from statistically overrepresented, evolutionarily conserved regulatory region motifs from mammalian genomes. JASPAR phyloFACTS serves as a non-redundant extension to JASPAR CORE, enhancing the overall breadth of JASPAR for promoter sequence analysis. The new release of JASPAR is available at http://jaspar.genereg.net.
- Publication
Nucleic acids research, 2006, Vol 34, Issue Database issue, pD95
- ISSN
1362-4962
- Publication type
Journal Article
- DOI
10.1093/nar/gkj115