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- Title
ConSite: web-based prediction of regulatory elements using cross-species comparison.
- Authors
Sandelin, Albin; Wasserman, Wyeth W; Lenhard, Boris
- Abstract
ConSite is a user-friendly, web-based tool for finding cis-regulatory elements in genomic sequences. Predictions are based on the integration of binding site prediction generated with high-quality transcription factor models and cross-species comparison filtering (phylogenetic footprinting). By incorporating evolutionary constraints, selectivity is increased by an order of magnitude as compared to single-sequence analysis. ConSite offers several unique features, including an interactive expert system for retrieving orthologous regulatory sequences. Programming modules and biological databases that form the foundation of the ConSite service are freely available to the research community. ConSite is available at http:/www.phylofoot.org/consite.
- Publication
Nucleic acids research, 2004, Vol 32, Issue Web Server issue, pW249
- ISSN
1362-4962
- Publication type
Journal Article
- DOI
10.1093/nar/gkh372