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- Title
EICO (Expression-based Imprint Candidate Organizer): finding disease-related imprinted genes.
- Authors
Nikaido, Itoshi; Saito, Chika; Wakamoto, Akiko; Tomaru, Yasuhiro; Arakawa, Takahiro; Hayashizaki, Yoshihide; Okazaki, Yasushi
- Abstract
We have developed an integrated database that is specialized for the study of imprinted disease genes. The database contains novel candidate imprinted genes identified by the RIKEN full-length mouse cDNA microarray study, information on validated single nucleotide polymorphisms (SNPs) to confirm imprinting using reciprocal mouse crosses and the predicted physical position of imprinting-related disease loci in the mouse and human genomes. It has two user-friendly search interfaces: the SNP-central view (MuSCAT: MoUse SNP CATalog) and the candidate gene-central view (CITE: Candidate Imprinted Transcripts by Expression). The database, EICO (Expression-based Imprint Candidate Organizer), can be accessed via the World Wide Web (http://fantom2.gsc.riken.jp/EICODB/) and the DAS client software. These data and interfaces facilitate understanding of the mechanism of imprinting in mammalian inherited traits.
- Publication
Nucleic acids research, 2004, Vol 32, Issue Database issue, pD548
- ISSN
1362-4962
- Publication type
Journal Article
- DOI
10.1093/nar/gkh093