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- Title
Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis.
- Authors
Lee, Chee Khoon; Brown, Chris; Gralla, Richard J; Hirsh, Vera; Thongprasert, Sumitra; Tsai, Chun-Ming; Tan, Eng Huat; Ho, James Chung-Man; Chu, Da Tong; Zaatar, Adel; Osorio Sanchez, Jemela Anne; Vu, Vu Van; Au, Joseph Siu Kie; Inoue, Akira; Lee, Siow Ming; Gebski, Val; Yang, James Chih-Hsin
- Abstract
The epidermal growth factor receptor (EGFR) signaling pathway is crucial for regulating tumorigenesis and cell survival and may be important in the development and progression of non-small cell lung cancer (NSCLC). We examined the impact of EGFR-tyrosine kinase inhibitors (TKIs) on progression-free survival (PFS) and overall survival (OS) in advanced NSCLC patients with and without EGFR mutations.
- Publication
Journal of the National Cancer Institute, 2013, Vol 105, Issue 9, p595
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djt072