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- Title
Estrogen metabolism and risk of breast cancer in postmenopausal women.
- Authors
Fuhrman, Barbara J; Schairer, Catherine; Gail, Mitchell H; Boyd-Morin, Jennifer; Xu, Xia; Sue, Laura Y; Buys, Saundra S; Isaacs, Claudine; Keefer, Larry K; Veenstra, Timothy D; Berg, Christine D; Hoover, Robert N; Ziegler, Regina G
- Abstract
Estrogens are recognized causal factors in breast cancer. Interindividual variation in estrogen metabolism may also influence the risk of breast cancer and could provide clues to mechanisms of breast carcinogenesis. Long-standing hypotheses about how estrogen metabolism might influence breast cancer have not been adequately evaluated in epidemiological studies because of the lack of accurate, reproducible, and high-throughput assays for estrogen metabolites.
- Publication
Journal of the National Cancer Institute, 2012, Vol 104, Issue 4, p326
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djr531