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Title
CYP2D6 inhibition and breast cancer recurrence in a population-based study in Denmark.
Authors
Lash, Timothy L; Cronin-Fenton, Deirdre; Ahern, Thomas P; Rosenberg, Carol L; Lunetta, Kathryn L; Silliman, Rebecca A; Garne, Jens Peter; Sørensen, Henrik Toft; Hellberg, Ylva; Christensen, Mariann; Pedersen, Lars; Hamilton-Dutoit, Stephen
Abstract
Cytochrome P450 2D6 (CYP2D6) inhibition reduces the concentration of 4-hydroxylated tamoxifen metabolites, but the clinical relevance remains uncertain.
Publication
Journal of the National Cancer Institute, 2011, Vol 103, Issue 6, p489