We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial.
- Authors
Elmets, Craig A; Viner, Jaye L; Pentland, Alice P; Cantrell, Wendy; Lin, Hui-Yi; Bailey, Howard; Kang, Sewon; Linden, Kenneth G; Heffernan, Michael; Duvic, Madeleine; Richmond, Ellen; Elewski, Boni E; Umar, Asad; Bell, Walter; Gordon, Gary B
- Abstract
Preclinical studies indicate that the enzyme cyclooxygenase 2 plays an important role in ultraviolet-induced skin cancers. We evaluated the efficacy and safety of celecoxib, a cyclooxygenase 2 inhibitor, as a chemopreventive agent for actinic keratoses, the premalignant precursor of nonmelanoma skin cancers, and for nonmelanoma skin cancers, including cutaneous squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs).
- Publication
Journal of the National Cancer Institute, 2010, Vol 102, Issue 24, p1835
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djq442