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Title
Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis.
Authors
Mocellin, Simone; Pasquali, Sandro; Rossi, Carlo R; Nitti, Donato
Abstract
Based on previous meta-analyses of randomized controlled trials (RCTs), the use of interferon alpha (IFN-alpha) in the adjuvant setting improves disease-free survival (DFS) in patients with high-risk cutaneous melanoma. However, RCTs have yielded conflicting data on the effect of IFN-alpha on overall survival (OS).
Publication
Journal of the National Cancer Institute, 2010, Vol 102, Issue 7, p493