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- Title
Risks of Lynch syndrome cancers for MSH6 mutation carriers.
- Authors
Baglietto, Laura; Lindor, Noralane M; Dowty, James G; White, Darren M; Wagner, Anja; Gomez Garcia, Encarna B; Vriends, Annette H J T; Cartwright, Nicola R; Barnetson, Rebecca A; Farrington, Susan M; Tenesa, Albert; Hampel, Heather; Buchanan, Daniel; Arnold, Sven; Young, Joanne; Walsh, Michael D; Jass, Jeremy; Macrae, Finlay; Antill, Yoland; Winship, Ingrid M; Giles, Graham G; Goldblatt, Jack; Parry, Susan; Suthers, Graeme; Leggett, Barbara; Butz, Malinda; Aronson, Melyssa; Poynter, Jenny N; Baron, John A; Le Marchand, Loic; Haile, Robert; Gallinger, Steve; Hopper, John L; Potter, John; de la Chapelle, Albert; Vasen, Hans F; Dunlop, Malcolm G; Thibodeau, Stephen N; Jenkins, Mark A; Dutch Lynch Syndrome Study Group
- Abstract
Germline mutations in MSH6 account for 10%-20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain.
- Publication
Journal of the National Cancer Institute, 2010, Vol 102, Issue 3, p193
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djp473