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- Title
Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves.
- Authors
Gil, Ziv; Cavel, Oren; Kelly, Kaitlyn; Brader, Peter; Rein, Avigail; Gao, Sizhi P; Carlson, Diane L; Shah, Jatin P; Fong, Yuman; Wong, Richard J
- Abstract
The ability of cancer to infiltrate along nerves is a common clinical observation in pancreas, head and neck, prostate, breast, and gastrointestinal carcinomas. For these tumors, nerves may provide a conduit for local cancer progression into the central nervous system. Although neural invasion is associated with poor outcome, the mechanism that triggers it is unknown.
- Publication
Journal of the National Cancer Institute, 2010, Vol 102, Issue 2, p107
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djp456