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- Title
Rituximab maintenance for the treatment of patients with follicular lymphoma: systematic review and meta-analysis of randomized trials.
- Authors
Vidal, Liat; Gafter-Gvili, Anat; Leibovici, Leonard; Dreyling, Martin; Ghielmini, Michele; Hsu Schmitz, Shu-Fang; Cohen, Amos; Shpilberg, Ofer
- Abstract
Follicular lymphoma is characterized by slow growth and an initially high rate of response to treatment, but patients typically relapse and experience progressive disease. Rituximab in combination with chemotherapy has been shown to improve overall survival in patients with follicular lymphoma compared with chemotherapy alone, but data from randomized clinical trials evaluating rituximab maintenance treatment in these patients are limited. We aimed to evaluate the effect of maintenance treatment with rituximab on the overall survival of patients with follicular lymphoma.
- Publication
Journal of the National Cancer Institute, 2009, Vol 101, Issue 4, p248
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djn478