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- Title
Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers.
- Authors
Eisen, Andrea; Lubinski, Jan; Gronwald, Jacek; Moller, Pal; Lynch, Henry T; Klijn, Jan; Kim-Sing, Charmaine; Neuhausen, Susan L; Gilbert, Lucy; Ghadirian, Parviz; Manoukian, Siranoush; Rennert, Gad; Friedman, Eitan; Isaacs, Claudine; Rosen, Eliot; Rosen, Barry; Daly, Mary; Sun, Ping; Narod, Steven A; Hereditary Breast Cancer Clinical Study Group
- Abstract
Hormone therapy (HT) is commonly given to women to alleviate the climacteric symptoms associated with menopause. There is concern that this treatment may increase the risk of breast cancer. The potential association of HT and breast cancer risk is of particular interest to women who carry a mutation in BRCA1 because they face a high lifetime risk of breast cancer and because many of these women take HT after undergoing prophylactic surgical oophorectomy at a young age.
- Publication
Journal of the National Cancer Institute, 2008, Vol 100, Issue 19, p1361
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djn313