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- Title
Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer.
- Authors
Ottewell, Penelope D; Mönkkönen, Hannu; Jones, Mark; Lefley, Diane V; Coleman, Robert E; Holen, Ingunn
- Abstract
The potent antiresorptive drug zoledronic acid (Zol) enhances the antitumor effects of chemotherapy agents in vitro. We investigated the effects of clinically achievable doses of doxorubicin (Dox) and Zol, given alone, in sequence, and in combination, on the growth of established breast tumors in vivo.
- Publication
Journal of the National Cancer Institute, 2008, Vol 100, Issue 16, p1167
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djn240