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- Title
Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth.
- Authors
Merritt, William M; Lin, Yvonne G; Spannuth, Whitney A; Fletcher, Mavis S; Kamat, Aparna A; Han, Liz Y; Landen, Charles N; Jennings, Nicholas; De Geest, Koen; Langley, Robert R; Villares, Gabriel; Sanguino, Angela; Lutgendorf, Susan K; Lopez-Berestein, Gabriel; Bar-Eli, Menashe M; Sood, Anil K
- Abstract
Interleukin-8 (IL-8) is a proangiogenic cytokine that is overexpressed in many human cancers. We investigated the clinical and biologic significance of IL-8 in ovarian carcinoma using human samples and orthotopic mouse models.
- Publication
Journal of the National Cancer Institute, 2008, Vol 100, Issue 5, p359
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djn024