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- Title
Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).
- Authors
Kaaks, Rudolf; Berrino, Franco; Key, Timothy; Rinaldi, Sabina; Dossus, Laure; Biessy, Carine; Secreto, Giorgio; Amiano, Pilar; Bingham, Sheila; Boeing, Heiner; Bueno de Mesquita, H Bas; Chang-Claude, Jenny; Clavel-Chapelon, Françoise; Fournier, Agnès; van Gils, Carla H; Gonzalez, Carlos A; Gurrea, Aurelio Barricarte; Critselis, Elena; Khaw, Kay Tee; Krogh, Vittorio; Lahmann, Petra H; Nagel, Gabriele; Olsen, Anja; Onland-Moret, N Charlotte; Overvad, Kim; Palli, Domenico; Panico, Salvatore; Peeters, Petra; Quirós, J Ramón; Roddam, Andrew; Thiebaut, Anne; Tjønneland, Anne; Chirlaque, Ma Dolores; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Tumino, Rosario; Vineis, Paolo; Norat, Teresa; Ferrari, Pietro; Slimani, Nadia; Riboli, Elio
- Abstract
Contrasting etiologic hypotheses about the role of endogenous sex steroids in breast cancer development among premenopausal women implicate ovarian androgen excess and progesterone deficiency, estrogen excess, estrogen and progesterone excess, and both an excess or lack of adrenal androgens (dehydroepiandrosterone [DHEA] or its sulfate [DHEAS]) as risk factors. We conducted a case-control study nested within the European Prospective Investigation into Cancer and Nutrition cohort to examine associations among premenopausal serum concentrations of sex steroids and subsequent breast cancer risk.
- Publication
Journal of the National Cancer Institute, 2005, Vol 97, Issue 10, p755
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/dji132