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- Title
Randomized trial of intraportal and/or systemic adjuvant chemotherapy in patients with colon carcinoma.
- Authors
Labianca, Roberto; Fossati, Roldano; Zaniboni, Alberto; Torri, Valter; Marsoni, Silvia; Nitti, Donato; Boffi, Lamberto; Scatizzi, Marco; Tardio, Berardino; Mastrodonato, Nicola; Banducci, Stefano; Consani, Giampiero; Pancera, Gianfranco; ACOI/GIVIO/GISCAD Investigators
- Abstract
5-fluorouracil-based adjuvant chemotherapy after surgical resection of colon cancer is standard treatment. However, the choice of best delivery route--that is, systemic (i.e., intravenous or oral) or regional (i.e., intraportal, intraperitoneal, or hepatic arterial infusion)--has been controversial. In a randomized clinical trial of patients with colon cancer, we compared the benefits of chemotherapy delivered by these routes individually or in combination.
- Publication
Journal of the National Cancer Institute, 2004, Vol 96, Issue 10, p750
- ISSN
1460-2105
- Publication type
Journal Article
- DOI
10.1093/jnci/djh132