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- Title
Overdiagnosis due to prostate-specific antigen screening: lessons from U.S. prostate cancer incidence trends.
- Authors
Etzioni, Ruth; Penson, David F; Legler, Julie M; di Tommaso, Dante; Boer, Rob; Gann, Peter H; Feuer, Eric J
- Abstract
Overdiagnosis of clinically insignificant prostate cancer is considered a major potential drawback of prostate-specific antigen (PSA) screening. Quantitative estimates of the magnitude of this problem are, however, lacking. We estimated rates of prostate cancer overdiagnosis due to PSA testing that are consistent with the observed incidence of prostate cancer in the United States from 1988 through 1998. Overdiagnosis was defined as the detection of prostate cancer through PSA testing that otherwise would not have been diagnosed within the patient's lifetime.
- Publication
Journal of the National Cancer Institute, 2002, Vol 94, Issue 13, p981
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/94.13.981