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- Title
Effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin.
- Authors
Ross, R K; Paganini-Hill, A; Wan, P C; Pike, M C
- Abstract
Hormone replacement therapy (HRT) given as unopposed estrogen replacement therapy (ERT) gained widespread popularity in the United States in the 1960s and 1970s. Recent prescribing practices have favored combination HRT (CHRT), i.e., adding a progestin to estrogen for the entire monthly cycle (continuous combined replacement therapy [CCRT]) or a part of the cycle (sequential estrogen plus progestin therapy [SEPRT]). Few data exist on the association between CHRT and breast cancer risk. We determined the effects of CHRT on a woman's risk of developing breast cancer in a population-based, case-control study.
- Publication
Journal of the National Cancer Institute, 2000, Vol 92, Issue 4, p328
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/92.4.328