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- Title
Diurnal cortisol rhythm as a predictor of breast cancer survival.
- Authors
Sephton, S E; Sapolsky, R M; Kraemer, H C; Spiegel, D
- Abstract
: Abnormal circadian rhythms have been observed in patients with cancer, but the prognostic value of such alterations has not been confirmed. We examined the association between diurnal variation of salivary cortisol in patients with metastatic breast cancer and subsequent survival. We explored relationships between cortisol rhythms, circulating natural killer (NK) cell counts and activity, prognostic indicators, medical treatment, and psychosocial variables.
- Publication
Journal of the National Cancer Institute, 2000, Vol 92, Issue 12, p994
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/92.12.994