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- Title
EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer. For the EUropean Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups.
- Authors
van Zandwijk, N; Dalesio, O; Pastorino, U; de Vries, N; van Tinteren, H
- Abstract
Preclinical evidence suggests that retinoids and antioxidants may prevent or delay the occurrence of cancer in the upper or lower airways, but such effects have not been reliably established in clinical studies. To assess the chemopreventive effects of vitamin A (retinyl palmitate) and N-acetylcysteine, we conducted a large randomized intervention study in patients with head and neck cancer or with lung cancer, most of whom had a history of smoking.
- Publication
Journal of the National Cancer Institute, 2000, Vol 92, Issue 12, p977
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/92.12.977