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- Title
Early age at smoking initiation and tobacco carcinogen DNA damage in the lung.
- Authors
Wiencke, J K; Thurston, S W; Kelsey, K T; Varkonyi, A; Wain, J C; Mark, E J; Christiani, D C
- Abstract
DNA adducts formed as a consequence of exposure to tobacco smoke may be involved in carcinogenesis, and their presence may indicate a high risk of lung cancer. To determine whether DNA adducts can be used as a "dosimeter" for cancer risk, we measured the adduct levels in nontumorous lung tissue and blood mononuclear cells from patients with lung cancer, and we collected data from the patients on their history of smoking.
- Publication
Journal of the National Cancer Institute, 1999, Vol 91, Issue 7, p614
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/91.7.614