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Title
Biologic and biochemical analyses of p16(INK4a) mutations from primary tumors.
Authors
Yarbrough, W G; Buckmire, R A; Bessho, M; Liu, E T
Abstract
Point mutations in the tumor suppressor gene p16(INK4a) (also known as p16, CDKN2, MTS1, and INK4a) are found in many tumor types. Because the function of the products of these naturally occurring mutants has not been fully explored, we investigated the functional activities of a wide range of naturally occurring p16 mutant proteins.
Publication
Journal of the National Cancer Institute, 1999, Vol 91, Issue 18, p1569