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- Title
Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma.
- Authors
Cordon-Cardo, C; Koff, A; Drobnjak, M; Capodieci, P; Osman, I; Millard, S S; Gaudin, P B; Fazzari, M; Zhang, Z F; Massague, J; Scher, H I
- Abstract
The p27KIP1 gene, whose protein product is a negative regulator of the cell cycle, is a potential tumor suppressor gene; however, no tumor-specific mutations of this gene have been found in humans. This study was undertaken to identify and to assess potential alterations of p27KIP1 gene expression in patients with benign prostatic hyperplasia (BPH) and patients with prostate cancer.
- Publication
Journal of the National Cancer Institute, 1998, Vol 90, Issue 17, p1284
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/90.17.1284