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- Title
Suppression of human colorectal mucosal prostaglandins: determining the lowest effective aspirin dose.
- Authors
Ruffin, M T, 4th; Krishnan, K; Rock, C L; Normolle, D; Vaerten, M A; Peters-Golden, M; Crowell, J; Kelloff, G; Boland, C R; Brenner, D E
- Abstract
A variety of studies have supported the finding that regular intake of aspirin (acetylsalicylic acid) or nonsteroidal anti-inflammatory agents can affect colorectal cancer carcinogenesis. These agents inhibit the synthesis of prostaglandins. High levels of prostaglandins are observed in colon cancer tissues.
- Publication
Journal of the National Cancer Institute, 1997, Vol 89, Issue 15, p1152
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/89.15.1152