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- Title
Risk of basal cell and squamous cell skin cancers after ionizing radiation therapy. For The Skin Cancer Prevention Study Group.
- Authors
Karagas, M R; McDonald, J A; Greenberg, E R; Stukel, T A; Weiss, J E; Baron, J A; Stevens, M M
- Abstract
Human evidence that ionizing radiation is carcinogenic first came from reports of nonmelanoma skin cancers (NMSCs) on the hands of workers using early radiation devices. An increased risk of NMSC has been observed among uranium miners, radiologists, and individuals treated with x rays in childhood for tinea capitis (ringworm of the scalp) or for thymic enlargement; NMSC is one of the cancers most strongly associated with the atomic bombing of Hiroshima and Nagasaki. Although exposure to ionizing radiation is a known cause of NMSC, it is not yet clear whether therapeutic radiation causes both major histologic types of NMSC, basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Additionally, the potentially modifying effects, such as latency, age when treated, and type of treatment, are not well understood.
- Publication
Journal of the National Cancer Institute, 1996, Vol 88, Issue 24, p1848
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/88.24.1848