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- Title
Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status.
- Authors
Diel, I J; Kaufmann, M; Costa, S D; Holle, R; von Minckwitz, G; Solomayer, E F; Kaul, S; Bastert, G
- Abstract
Approximately 30% of the patients with primary breast cancer who have no axillary lymph node involvement (i.e., lymph node negative) at the time of surgery will relapse within 10 years; 10%-20% of the patients with distant metastases will be lymph node negative at surgery. Axillary lymph node dissection, as a surgical procedure, is associated with frequent complications. A possible alternative to nodal dissection in terms of prognosis may be the immunocytochemical detection of tumor cells in bone marrow.
- Publication
Journal of the National Cancer Institute, 1996, Vol 88, Issue 22, p1652
- ISSN
0027-8874
- Publication type
Journal Article
- DOI
10.1093/jnci/88.22.1652