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- Title
Synergy of the antibiotic colistin with echinocandin antifungals in Candida species.
- Authors
Zeidler, Ute; Bougnoux, Marie-Elisabeth; Lupan, Alexandru; Helynck, Olivier; Doyen, Antonia; Garcia, Zacarias; Sertour, Natacha; Clavaud, Cécile; Munier-Lehmann, Hélène; Saveanu, Cosmin; d'Enfert, Christophe
- Abstract
Candida albicans is the most prevalent fungal pathogen of humans, causing a wide range of infections from harmless superficial to severe systemic infections. Improvement of the antifungal arsenal is needed since existing antifungals can be associated with limited efficacy, toxicity and antifungal resistance. Here we aimed to identify compounds that act synergistically with echinocandin antifungals and that could contribute to a faster reduction of the fungal burden.
- Publication
The Journal of antimicrobial chemotherapy, 2013, Vol 68, Issue 6, p1285
- ISSN
1460-2091
- Publication type
Journal Article
- DOI
10.1093/jac/dks538