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- Title
Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics.
- Authors
Guzman, Juan David; Wube, Abraham; Evangelopoulos, Dimitrios; Gupta, Antima; Hüfner, Antje; Basavannacharya, Chandrakala; Rahman, Md Mukhleshur; Thomaschitz, Christina; Bauer, Rudolf; McHugh, Timothy Daniel; Nobeli, Irene; Prieto, Jose M; Gibbons, Simon; Bucar, Franz; Bhakta, Sanjib
- Abstract
The aim of this study was to comprehensively evaluate the antibacterial activity and MurE inhibition of a set of N-methyl-2-alkenyl-4-quinolones found to inhibit the growth of fast-growing mycobacteria.
- Publication
The Journal of antimicrobial chemotherapy, 2011, Vol 66, Issue 8, p1766
- ISSN
1460-2091
- Publication type
Journal Article
- DOI
10.1093/jac/dkr203