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- Title
Whole-genome comparison of two Acinetobacter baumannii isolates from a single patient, where resistance developed during tigecycline therapy.
- Authors
Hornsey, Michael; Loman, Nick; Wareham, David W; Ellington, Matthew J; Pallen, Mark J; Turton, Jane F; Underwood, Anthony; Gaulton, Tom; Thomas, Claire P; Doumith, Michel; Livermore, David M; Woodford, Neil
- Abstract
The whole genomes of two Acinetobacter baumannii isolates recovered from a single patient were sequenced to gain insight into the nature and extent of genomic plasticity in this important nosocomial pathogen over the course of a short infection. The first, AB210, was recovered before tigecycline therapy and was susceptible to this agent; the second, AB211, was recovered after therapy and was resistant.
- Publication
The Journal of antimicrobial chemotherapy, 2011, Vol 66, Issue 7, p1499
- ISSN
1460-2091
- Publication type
Journal Article
- DOI
10.1093/jac/dkr168