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- Title
Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181.
- Authors
Triana-Baltzer, Gallen B; Sanders, Rebecca L; Hedlund, Maria; Jensen, Kellie A; Aschenbrenner, Laura M; Larson, Jeffrey L; Fang, Fang
- Abstract
influenza viruses (IFVs) frequently achieve resistance to antiviral drugs, necessitating the development of compounds with novel mechanisms of action. DAS181 (Fludase), a sialidase fusion protein, may have a reduced potential for generating drug resistance due to its novel host-targeting mechanism of action.
- Publication
The Journal of antimicrobial chemotherapy, 2011, Vol 66, Issue 1, p15
- ISSN
1460-2091
- Publication type
Journal Article
- DOI
10.1093/jac/dkq387