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- Title
Failure and relapse after treatment with trimethoprim/sulfamethoxazole in classic Whipple's disease.
- Authors
Lagier, Jean-Christophe; Fenollar, Florence; Lepidi, Hubert; Raoult, Didier
- Abstract
Classic Whipple's disease is a chronic disease caused by Tropheryma whipplei. A recent study reported that intravenous treatment with ceftriaxone or meropenem followed by a 1 year treatment with trimethoprim/sulfamethoxazole cured all patients. However, we have previously reported that T. whipplei is poorly susceptible to beta-lactams and resistant to trimethoprim. Herein, we want to evaluate these antibiotic regimens.
- Publication
The Journal of antimicrobial chemotherapy, 2010, Vol 65, Issue 9, p2005
- ISSN
1460-2091
- Publication type
Journal Article
- DOI
10.1093/jac/dkq263